Product Name:N-Acetyl-L-Cysteine Powder
Other Name:NAC Powder
Appearance:White powder
Specification:99%
CAS:616-91-1
Sample:10-50g Sample For free
MOQ:1kg
Certificate:ISO22000, Kosher, Halal, EU, USDA, HACCP, FSSC 22000, Organic,FAD
OEM Service:Private label and Customized package
N-acetyl cysteine (NAC) is a supplement form of cysteine, a conditionally essential amino acid. NAC has many health benefits, including replenishing antioxidants and nourishing your brain.
NAC is considered ‘conditionally essential’ because your body can produce it from other amino acids. It becomes essential only when the dietary intake of methionine and serine is low.
Cysteine is found in most high protein foods, such as chicken, turkey, yogurt, cheese, eggs, sunflower seeds, and legumes.
Consuming adequate cysteine and NAC is important for various health reasons, including replenishing the most potent antioxidant in your body, glutathione. These amino acids also help with chronic respiratory conditions, fertility, and brain health.
N-Acetyl-L-Cysteine, also known as N-Acetyl Cysteine or N acetyl cysteine, is an amino acid common in vivo, can be transformed from the body of methionine, cystine can be transformed with each other, N-acetyl Cysteine is made of L-cysteine.
Product Name | N-Acetyl-L-Cysteine Powder |
Other Name | NAC Powder |
Specification | 99% |
Appearance | White powder |
CAS No | 616-91-1 |
COA | Avaialble |
Grade | Food Grade |
Certificate | Kosher, Halal, EU, USDA, HACCP, FSSC 22000, Organic,FAD,QS |
Sample | 10-50g Sample For free |
MOQ | 1kg |
OEM Service | Private label and Customized package |
Packaging | 1-5kg/25kg(aluminum foil bag/carton/cardboard drum) |
Shelf life | 2 year,Available InBulk, Private Label/OEM, Individually Packaged Goods |
N-acetylcysteine acts on its own as an antioxidant and is also used for the formation of glutathione. The amino acids cysteine, glycine, and glutamic acid combine to form glutathione, the body’s primary antioxidant.
Low glutathione levels can lead to premature aging, excessive free radical production, and difficulty with phase I detoxification.
Cysteine is the rate-limiting amino acid, meaning if you don’t consume enough of it, you can’t produce enough glutathione.
The liver, lungs, and kidneys produce the most glutathione. Glutathione is built inside our cells with the three amino acids mentioned above. It cannot get transferred from the outside of the cell to inside of it, so supplementing with glutathione itself doesn’t seem to work well. Instead, you’re better off taking NAC to support glutathione capacity.
Multiple research studies show NAC has a positive impact on respiratory health. It’s often recommended as a mucolytic agent, meaning it helps break down mucus in our airways for both acute and chronic conditions that affect breathing.
Both a systematic review and a meta-analysis of clinical trials suggest NAC may be particularly helpful for reducing the frequency and duration of bronchitis symptoms in those with chronic, recurring bronchitis.
Evidence also suggests regular use of NAC seems to improve lung function in those with chronic obstructive pulmonary disease (COPD).
NAC may also help with other inflammation-related breathing conditions, such as asthma and nasal sinus infection; it’s even been shown to have protective effects in smokers.
The liver is our primary detoxification organ, and it relies heavily on adequate glutathione antioxidant capacity to protect itself from the potentially harmful effects of unstable compounds that are either ingested or produced by the body.
NAC is one of several compounds known to promote the activity of certain phase I detoxification enzymes our liver relies on to neutralize and filter out waste products or toxins from circulation.
It’s also been shown to help reduce the negative effects of non-alcoholic fatty liver disease, or NAFLD, the most common chronic liver disease in the United States that affects as many as one in three adults.
In one well-designed study of elderly subjects, 600 mg of NAC taken twice daily appeared to significantly reduce symptoms of viral respiratory illnesses (influenza), even though it did not reduce the risk of becoming infected.
However, another interesting study did show that a combination of NAC and L-theanine significantly reduced the incidence of the common cold and fevers, though it had no apparent effect on the duration of the cold.
A meta-analysis of NAC’s effects during acute respiratory distress syndrome (ARDS), which often requires risky and costly hospital management in intensive care units (ICUs), found that patients treated with NAC had shorter ICU stays than those not given the supplement. Interestingly, the short term and 30-day mortality were not different between the two groups, but the duration of ICU stays were significantly shorter in the NAC group.
While NAC may not be a “magic bullet,” it may help reduce the demand for critical care.
Encouraging results like these show the need for further research on dietary supplements and immune health.
Perhaps related to NAC’s antioxidant function, it appears to mitigate cognitive disturbance of neuroinflammation in healthy subjects and those with other neurological disorders (including trauma, Alzheimer’s disease, Parkinson’s disease, and drug use).
Although the specific mechanisms behind NAC’s cognitive benefits are not well understood, it appears to be helpful as an individual supplement and in combination with other antioxidants, such as alpha-lipoic acid, vitamin A, vitamin E, and omega-3s.
Some research shows NAC supplementation reduces compulsive behavior, such as hair pulling, skin picking, and other obsessive-compulsive behaviors. It also shows promise as a treatment for substance abuse and withdrawal in those with cocaine addiction.
A meta-analysis of several clinical studies concluded that NAC helps reduce depressive symptoms and improve overall cognitive function and was well tolerated.
Dietary cysteine intake appears to be inversely associated with ischemic stroke in women, meaning women with higher dietary cysteine intakes tend to have fewer strokes.
Supplemental NAC has been studied as a potential treatment option for several cardiovascular disease conditions, in addition to existing standard treatments, for its role in helping support nitric oxide production and endothelial function. One study of patients in end-stage renal failure showed 600 mg of NAC twice daily reduced heart attack or stroke as compared to a placebo.
Researchers gave NAC in doses of 1,200 mg per day, 600 mg per day, or a placebo to three different groups of patients who all had COPD and elevated C-reactive protein (one of the most common measures of systemic inflammation).
After 10 days, 90 percent of those who took 1,200 mg per day, 52 percent of those who took 600 mg, and 19 percent of the placebo group saw their C-reactive protein levels return to normal.
In another study, the use of 1.8 grams of NAC per day lowered homocysteine levels — another marker of systemic inflammation — by 11.7 percent. Elevated homocysteine, like C-reactive protein, is considered a risk factor for cardiovascular disease.
There is no specific recommended intake for cysteine, as the body can produce small amounts. To synthesize the amino acid cysteine, the body requires adequate levels of folate, vitamin B6, and vitamin B12. These nutrients are found in foods such as beans, lentils, spinach, bananas, salmon, and tuna. While most protein-rich foods, including chicken, yogurt, cheese, eggs, sunflower seeds, and legumes, contain cysteine, some individuals choose to supplement with NAC to boost their cysteine levels.
NAC has low bioavailability, meaning it is not well absorbed by the body. The generally accepted daily supplementation dose ranges from 600 to 1,800 mg of NAC. NAC can be administered via intravenous (IV) injection, aerosol spray, or taken orally in liquid or powder form.
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