Active Ingredient: Fisetin
Specification: 50%, 85% ,98%
Appearance: Yellow fine powder
Botanical Source: Cotinus Coggygria Scop
Test Method: HPLC
Certificate: ISO22000, Kosher, Halal, Organic(EU), USDA, FSSC 22000, FDA, SGS
Sample: 5-50g Sample for free
MOQ: 1kg
OEM Service: Private label and Customized package
Our premium Cotinus Coggygria Extract, commonly known as Smoketree Extract. This potent botanical derivative is standardized to high-purity Fisetin, a naturally occurring flavonol that has captured the attention of the global anti-aging and cognitive health sectors.
What is Fisetin?
At the heart of this extract lies the bioactive compound Fisetin (7,3′,4′-trihydroxyflavone). Unlike generic antioxidants, Fisetin is recognized as a premier senolytic. In simpler terms, it acts as a “cellular scout,” identifying and helping the body clear out senescent cells—often called “zombie cells”—that accumulate with age and cause inflammation. By supporting DNA repair and boosting glutathione levels, this extract goes beyond basic nutrition; it’s a foundational tool for metabolic health and neurological clarity.
Market Landscape: Why Now?
The global market for Fisetin Powder is currently witnessing a massive surge, driven by the “Longevity Revolution.” As consumers move away from general multivitamins toward targeted, science-backed molecules, Fisetin has emerged as a top-tier ingredient alongside NMN and Resveratrol. Current demand is high in the dietary supplement, functional food, and nutricosmetic industries, making it a lucrative addition to any premium product line.
Our Cotinus Coggygria Extract Fisetin Powder offers 98% pure Fisetin with a clean, low-solvent profile, sourced from a fully traceable supply chain, and is available with flexible OEM options like custom micronization and Fisetin blends, making it simple to incorporate into capsules, powders, or other formulations.
1. Precision Purity with Production Control
Our process is designed for molecular precision, delivering consistently 98% fisetin content verified by strict analytical methods (e.g., HPLC). This level of purity matters for downstream effects like bioactivity, label claims, and dosage control—especially for high‑end nutraceuticals and longevity formulas that are sensitive to assay variation.
2. Controlled Raw Material Traceability
We source Cotinus coggygria wood and leaf internally through a vertically integrated supply chain, reducing the typical quality variability seen with wild‑harvested botanicals. By managing cultivation and harvesting practices, we effectively minimize pesticide residues and heavy metal concerns that often plague lower‑cost imports.
3. Low‑Residual Processing and Formulation Ease
Our proprietary extraction and refinement methods—refined over nearly **20 years of R&D and commercial manufacturing—**result in a fisetin powder with minimal solvent trace and neutral sensory profile. This matters in practice: product developers report fewer issues with off‑flavors or masking agents when formulating capsules, drink powders, or functional blends, saving reformulation cycles and cost.
4. OEM Integration That Doesn’t Stop at Shipping Powder
We go beyond bulk supply. Our OEM services include custom micronization for accelerated dissolution, mesh size tailoring for high‑speed encapsulation, and optional pre‑blends (e.g., fisetin + complementary flavonoids) that align with specific product strategies.
5. Manufacturing Scale for Reliability
With order fulfillment and production systems supported by decades of industry experience, we deliver stable supply at commercial scale—a crucial factor in a market where raw material scarcity and extraction inconsistency can lead to quarter‑to‑quarter pricing swings.
| Item | Specification | Test Method | Result |
| Appearance | Fine yellow to light brown powder | Visual | Conforms |
| Odor | Characteristic, mild | Organoleptic | Conforms |
| Active Ingredient (Fisetin) | ≥98% | HPLC | 98.30% |
| Loss on Drying | ≤5% | 105°C, 2h | 3.20% |
| Ash | ≤2% | AOAC 923.03 | 1.50% |
| Heavy Metals (Pb, As, Cd, Hg) | ≤10 ppm | ICP-MS | Pb <2 ppm, As <1 ppm, Cd <0.5 ppm, Hg <0.1 ppm |
| Residual Solvents (Ethanol, Methanol, Acetone) | Meet USP <467> | GC | Conforms |
| Particle Size | 100% through 80 mesh | Laser Diffraction | 95% through 80 mesh |
| Microbial Limit | Total Plate Count ≤1000 CFU/g | AOAC 990.12 | 320 CFU/g |
| Yeast & Mold | ≤100 CFU/g | AOAC 997.02 | <10 CFU/g |
| E. coli | Negative | USP 2022 | Negative |
| Salmonella | Negative | USP 2022 | Negative |
| Solubility | Soluble in DMSO, ethanol; slightly soluble in water | Visual | Conforms |
| pH (1% solution) | 5.0–7.0 | pH meter | 6.2 |
Q: How pure is the Fisetin in your extract?
A: Our standard product contains ≥98% Fisetin, verified by HPLC, ensuring consistent potency and reproducibility.
Q: Is the extract safe for food and supplement applications?
A: Yes, our product meets heavy metal and microbial limits compliant with international standards (USP, EU, and FDA guidelines).
Q: Can it dissolve in water or beverages?
A: Fisetin is slightly soluble in water but soluble in ethanol or DMSO. We offer micronized options for better solubility in drink formulations.
Q: How to prevent sedimentation or instability in liquid products?
A: Use micronized powder, stabilizers, or emulsifiers; our OEM services can provide pre-blended fisetin formulations for better dispersion.
Q: Are there synergistic combinations with other ingredients?
A: Yes, Fisetin can be combined with quercetin, resveratrol, or other polyphenols for enhanced antioxidant and anti-aging effects; we can provide custom blends for your brand.
Q: What certifications and traceability are available?
A: Our extract comes from a vertically integrated supply chain, with documentation for farm-to-powder traceability, and optional certificates including ISO, cGMP, and organic certifications.
1. Longevity and Senescence
Fisetin powder is often associated with healthy aging because of its unique ability to support the natural process of cellular renewal. As we age, our bodies accumulate senescent cells. These cells can linger in tissues, releasing substances that create stress and accelerate the aging process. Fisetin powder appears to help the body manage this buildup by encouraging the natural clearance.
2. Cognitive Function and Brain Health
One of the most appealing aspects of Fisetin powder is its potential to support brain health and protect against age-related cognitive decline. The brain, like any other organ, is affected by the passage of time. Over the years, oxidative stress, inflammation, and the buildup of dysfunctional proteins can impact memory, learning, and overall clarity of thought. Fisetin powder helps by supporting the brain’s antioxidant defenses and calming inflammatory responses that interfere with communication between neurons. This creates a more stable environment for healthy brain function, enhanced by Fisetin powder.
3. Anti-inflammatory Effects
Inflammation is the body’s natural defense mechanism, but when it becomes chronic or widespread, it can do more harm than good. Ongoing inflammation is often linked to discomfort, stiffness, and many age-related health challenges. Fisetin powder’s natural anti-inflammatory properties help calm this unnecessary response, keeping the body’s defense system balanced. It works by reducing the release of signaling molecules that trigger inflammation and by protecting tissues from the wear and tear caused by ongoing inflammatory stress.
4. Antioxidant Properties
At its core, Fisetin powder is a powerful antioxidant, meaning it helps neutralize free radicals. Free radicals are a natural byproduct of everyday activities, but when their levels rise too high, they contribute to oxidative stress. This stress accelerates the aging process and wears down tissues throughout the body. Fisetin powder reduces oxidative stress and gives cells the support they need to stay healthy. By defending DNA, proteins, and cell membranes from damage, it helps maintain the integrity of the body’s systems.
5. Skin Health
The skin is often the first place where signs of aging become visible, and Fisetin powder offers unique support in this area. As we age, skin cells called fibroblasts can become senescent, losing their function and contributing to wrinkles, sagging, and dullness. Fisetin powder helps by encouraging the body to clear away these worn-out cells, making space for more active fibroblasts to thrive.
Partner with us for high-purity Cotinus Coggygria Extract Fisetin Powder. With nearly 20 years of manufacturing and R&D experience, our product meets multiple certifications including ISO and GMP. We offer stable bulk supply and flexible OEM services tailored to your brand needs. Contact us at info@botanicalcubesupplier.com to discuss your requirements.
Just send email to info@botanicalsuppliers.com, or submit your requirement in bottom form, we are of service at any time!
If you have any questions, please contact our experts.We are always ready to help you with individual formulations, private label solutions or any other requirements to kick-start your brand!