Chamomile Extract Apigenin Powder
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Product Description

Chamomile Extract Apigenin Powder – A Natural Source of High-Purity Apigenin

Chamomile Extract Apigenin Powder (Latin Name: Matricaria chamomilla L.) is a premium botanical ingredient designed to deliver the primary bioactive flavonoid of the chamomile flower in a highly concentrated form. Identified by CAS No. 520-36-5, this extract serves as a bridge between traditional herbal wisdom and modern nutritional science.

From Flower to Bioactive Crystal
While raw chamomile tea has been used for centuries, it contains only trace amounts of active compounds. Our extraction process isolates Apigenin (4′,5,7-Trihydroxyflavone) from the plant matrix, removing inert fibers and waxes. This results in a potent, yellow-to-pale-yellow powder available in specifications ranging from 1.2% (Standardized Extract) to 98% (High-Purity Isolate) via HPLC testing. This standardization ensures that every batch provides a consistent dosage, regardless of seasonal variations in the raw crop.

Mechanism of Action
Apigenin is scientifically recognized for its molecular ability to cross the blood-brain barrier. It acts primarily by modulating GABA receptors in the brain, which is the key biological mechanism behind its renowned calming and relaxation effects. Unlike synthetic sedatives, this natural interaction supports the nervous system without causing heavy drowsiness, making it a preferred choice for “Daytime Relaxation” or “Natural Sleep” formulations.

Why Choose Our Chamomile Extract Apigenin Powder

1. Apigenin-Focused Extraction, Not Generic Chamomile Powder

Most suppliers offer chamomile extracts standardized broadly to flavonoids or presented as whole-herb powders, where apigenin content can fluctuate significantly between batches.Our product is developed with a targeted apigenin enrichment strategy, allowing us to consistently control the active compound rather than relying on natural variance.This approach reduces formulation risk for manufacturers who need predictable performance in capsules, tablets, or cosmetic bases.

2. Optimized for Industrial Formulation, Not Just Lab Purity

High apigenin content alone does not guarantee a usable raw material. Many high-purity apigenin products on the market show poor dispersibility, strong bitterness, or dark coloration, which complicates downstream production.

Our Chamomile Extract Apigenin Powder is engineered to balance active concentration and processability:

  • Light yellow to off-white appearance, suitable for capsules and cosmetic emulsions
  • Lower botanical odor compared with conventional chamomile extracts
  • Improved powder flowability, reducing capsule weight deviation and tablet capping issues

3. OEM Integration Built Around Apigenin’s Functional Positioning

Unlike suppliers that treat apigenin as a standalone commodity, we develop this ingredient with OEM compatibility in mind. Chamomile Extract Apigenin Powder is frequently positioned in Sleep and relaxation formulas,Stress and mood-support supplements,Skin-soothing and anti-aging cosmetic systems.

Our OEM support goes beyond encapsulation. We assist with dose rationalization, synergistic ingredient pairing, and format adaptation, ensuring that apigenin’s functionality is preserved in the finished product.

COA

Test Item Specification Method Result
Appearance Off-white to pale yellow powder Visual Conforms
Odor Characteristic, mild Organoleptic Conforms
Identification Positive HPLC / UV Conforms
Assay (Apigenin) ≥ 98.0% HPLC 98.42%
Loss on Drying ≤ 2.0% USP <731> 0.68%
Residue on Ignition ≤ 1.0% USP <281> 0.21%
Particle Size ≥ 95% pass 80 mesh Sieve Analysis Conforms
Bulk Density 0.35 – 0.55 g/mL USP <616> 0.47 g/mL
Heavy Metals (Total) ≤ 10 ppm ICP-MS < 5 ppm
Lead (Pb) ≤ 3.0 ppm ICP-MS 0.42 ppm
Arsenic (As) ≤ 2.0 ppm ICP-MS 0.31 ppm
Cadmium (Cd) ≤ 1.0 ppm ICP-MS 0.09 ppm
Mercury (Hg) ≤ 0.1 ppm ICP-MS < 0.02 ppm
Total Plate Count ≤ 1,000 CFU/g USP <61> < 100 CFU/g
Yeast & Mold ≤ 100 CFU/g USP <61> < 20 CFU/g
E. coli Negative / 10 g USP <62> Negative
Salmonella Negative / 25 g USP <62> Negative
Residual Solvents Meet USP limits GC Conforms
Pesticide Residues Meet EU/USP limits GC-MS / LC-MS Conforms


Chamomile Extract Apigenin Benefits

  • Works as an Antioxidant

Flavonoids are widely known for their antioxidant properties, and a number of studies show that apigenin, in particular, has significant antioxidant effects. It’s also an effective anti-inflammatory agent compared to other flavonoids.Because of its antioxidant effects, the flavone is used to promote healthy aging and utilized to boost skin health. Topical apigenin is even used to fight acne and promote skin cell growth.

  • Supports Heart Health

Apigenin supports cardiovascular health by reducing blood pressure and inflammation. Animal models show that it has cardioprotective effects in rats with heart damage.One animal study found that apigenin protected rats against heart attack by reducing edema, cell death and oxidative stress.

  • Has Antimicrobial Effects

Reports suggest that apigenin has “reverse antibiotic” activities against some bacteria, which means that it may be active against antibiotic-resistant bacteria and help reverse bacterial resistance. Researchers believe that the phytonutrient could be a candidate as a new antibiotic or as a dietary supplement to enhance the performance of antibiotics.The nutrient also has proved to inhibit multiple viruses, including herpes; hepatitis C; influenza; hand, foot and mouth disease; and African swine fever.

  • Reduces Pain

Because of its anti-inflammatory effects, apigenin is able to reduce pain and discomfort related to inflammatory issues. This includes pain from digestive problems, infections, immune responses and migraine pain.The flavonoid has been shown to decrease the release of cytokines, which can overproduce and lead to disease.

  • Boosts Brain Function

Apigenin has neuroprotective effects.Research published in Neural Regeneration Research found that apigenin has cognition-enhancing effects because of its antioxidant and anti-inflammatory properties. In mice with Alzheimer’s disease, it was able to improve memory and learning deficits, and in humans it suppressed inflammatory mediators.

  • Fights Diabetes

Animal studies suggest that apigenin improves insulin resistance and can be helpful for people with diabetes. One report found that the flavone improved impaired glucose tolerance and significantly decreased insulin resistance.

  • May Increase Testosterone

Lab studies suggest that apigenin plays a role in testosterone synthesis and blocks signaling of testosterone repressing proteins.Because of its potential impact on hormone levels, it has become more popular to use apigenin for bodybuilding efforts. In this case, apigenin supplements are used to increase testosterone and potentially block estrogen production.This may help with muscle growth, strength and energy levels.

  • Eases Anxiety and Depression

This flavone is known for its relaxing and sedative effects. It has been shown to reduce cortisol levels, helping prevent the body’s response to chronic stress. This explains why chamomile tea can have beneficial effects on anxiety and help aid relaxation and sleep.Apigenin also has been shown to improve depression in rodents. Treatment with the flavone was able to elevate immobility time in mice that were induced by chronic corticosterone treatment.

Chamomile Extract Apigenin Powder Applications

  • Skincare & Cosmetics

Soothes irritated skin, reduces redness, and moisturizes in creams, serums & masks.
Relieves eczema, acne & sunburn with anti-inflammatory properties.
Added to shampoos & conditioners for scalp care.

  • Dietary Supplements & Functional Foods

Supports relaxation, digestion & sleep in capsules, teas & drink mixes.
Rich in apigenin, known for stress relief & sleep quality.

  • Pharmaceuticals & Traditional Medicine

Aids in wound healing & inflammation relief in ointments.
Treats bloating, indigestion & IBS.
Acts as a natural sedative for sleep support.

  • Pet Care Products

Soothes itchy skin in pet shampoos & balms.
Helps calm anxious pets in treats & supplements.

FAQs

1. Is apigenin the same as chamomile extract?
No. Apigenin is a specific flavonoid found in chamomile. Standard chamomile extract may contain very low and variable apigenin levels, while apigenin powder provides a standardized, measurable active.

2. Why choose chamomile-derived apigenin instead of synthetic apigenin?
Chamomile-sourced apigenin supports clean-label and plant-based positioning, with better market acceptance in supplements and cosmetics compared to synthetic isolates.

3. What is the difference between apigenin 95% and apigenin 98%?
The difference lies in purity and formulation control. Apigenin 98% offers lower dosage requirements, higher consistency, and easier standardization for premium products.

4. Is apigenin suitable for long-term use in supplements?
Apigenin is naturally present in commonly consumed foods and herbs. Standardized usage levels are widely applied in long-term wellness formulations, subject to regulatory compliance.

5. Does apigenin have solubility or formulation challenges?
Apigenin has limited water solubility. Proper particle size control, dispersion techniques, or blending strategies are recommended for uniform distribution in finished products.

6. Can apigenin be combined with other calming ingredients?
Yes. It is commonly formulated with magnesium, melatonin alternatives, L-theanine, valerian, or passionflower extracts to enhance relaxation-focused product positioning.

7. Is chamomile apigenin suitable for cosmetic formulations?
Yes. Its anti-inflammatory and soothing properties make it suitable for sensitive-skin and anti-aging cosmetic products when properly formulated.

Apigenin Powder Manufacturer & OEM

As a long-term Chamomile Extract Apigenin Powder manufacturer and bulk supplier, we work closely with supplement brands, contract manufacturers, and ingredient distributors to build stable, scalable supply relationships. This product’s core advantage lies in its high-purity apigenin content, controlled botanical sourcing, and formulation-ready performance, making it suitable for both finished-product manufacturing and further processing. Our production facilities operate under multiple internationally recognized certifications, ensuring consistent quality, traceability, and regulatory alignment across different markets. With nearly 20 years of experience in botanical extraction and OEM solutions, we support customized specifications, private-label development, and long-term bulk supply. For partnership inquiries, technical details, or OEM cooperation on apigenin-based products, please contact us at info@botanicalsuppliers.com.

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