Urolithin A Powder

Product Description

Urolithin A Powder for Mitochondrial Health & Healthy Aging

Urolithin A Powder, also known as Urolithin-A, UA powder, or Urolithin A bulk powder, is a high-value postbiotic ingredient widely used in anti-aging, mitochondrial health, and muscle vitality formulations. Unlike botanical extracts that rely on variable plant profiles, Urolithin A is a single, well-defined bioactive compound, making it highly suitable for standardized dietary supplement and functional nutrition products.

The core active component of this product is Urolithin A (CAS 1143-70-0), a natural metabolite derived from ellagitannins found in foods such as pomegranates and berries. In the human body, Urolithin A is produced through gut microbiota metabolism; however, only a small percentage of people can generate sufficient levels naturally.

Supplementing with Urolithin A powder bypasses this limitation, delivering direct, consistent bioavailability. Scientifically, Urolithin A is best known for its role in activating mitophagy, the cellular process that clears damaged mitochondria and supports energy metabolism at the cellular level.

In today’s longevity and healthy-aging market, Urolithin A has moved from a research-driven ingredient to a commercial priority. Demand is growing rapidly across: Anti-aging and longevity supplements,Muscle health and active aging formulas,Mitochondrial support and cellular energy products.

Urolithin A is not an agricultural extract. Its production requires precise chemical synthesis and purification, where batch consistency, residual control, and stability directly affect downstream formulation performance. Our advantage lies in tight control over purity specifications and batch-to-batch uniformity, which is critical for brands positioning Urolithin A as a science-backed, premium ingredient.

Second, when it comes to OEM and private-label manufacturing, Urolithin A presents formulation challenges such as low dosage accuracy, flowability, and compatibility with other actives (e.g., NMN, NAD⁺ boosters, spermidine). We design our Urolithin A powder specifications specifically for capsule, tablet, and sachet applications, helping brands reduce formulation risk and scale faster.

Finally, we support flexible OEM solutions, from bulk Urolithin A powder supply to finished dosage forms, aligned with regulatory and market positioning needs. This allows our partners to enter or expand in the Urolithin A supplement market without the trial-and-error costs typically associated with this ingredient.

Why Our Urolithin A Powder?

1. High-Purity, Single-Molecule Focused Manufacturing

Urolithin A is not a plant extract blend — it requires precise synthesis and deep purification.

Our Urolithin A Powder is produced with:
1) ≥98.0% purity (HPLC) as a standard commercial grade
2) Low residual solvent profile, aligned with EU and US dietary supplement expectations
3) Tight impurity control, critical for long-term mitochondrial health positioning

2. Consistent Batch-to-Batch Performance (Key for OEM Scale)

One of the biggest risks with Urolithin A bulk powder is batch variability, especially when scaling from pilot to commercial volumes.

We design our process to deliver:
1) Consistent particle size distribution, improving capsule and tablet weight accuracy
2) Stable bulk density, reducing fill variation in automated OEM lines
3) Reproducible assay values, minimizing re-validation work for repeat orders

3. Formulation-Ready Design for Low-Dose Actives

Urolithin A is typically used at 10–500 mg/day, depending on positioning. At these low dosages, poor flowability or segregation can cause serious OEM issues.

Our Urolithin A Powder is optimized for:
1) Uniform blending with NAD⁺ boosters (NMN, NR-Cl, NMNH)
2) Compatibility with spermidine, AKG, and polyphenol systems
3) Reduced agglomeration during mixing and encapsulation

4. OEM & Private Label Advantage Built Around Urolithin A

From a B-end perspective, Urolithin A is a high-cost, high-risk ingredient if OEM support is weak.

We provide:
1) Bulk powder supply + finished dosage OEM (capsules, tablets, sachets)
2) Flexible MOQ structures aligned with market testing and scale-up
30 Technical support for formulation positioning, not just raw material sales

5. Production & R&D Experience That Matches the Ingredient’s Complexity

With close to 20 years of production and R&D experience in functional actives, we understand that Urolithin A is not a “fast-copy” ingredient.

Our team supports:
1) Stability and shelf-life considerations for long distribution cycles
2) Documentation readiness for regulatory review and brand due diligence
3) Long-term supply planning for brands targeting repeat, annual SKUs

COA

Urolithin A Benefits

• Muscle Health

Studies indicate UA can promote muscle protein synthesis and potentially mitigate muscle atrophy, making it relevant to muscle health and performance.

• Cellular Health

UA has shown promise in enhancing mitochondrial function and promoting mitophagy (the recycling of damaged mitochondria), which is crucial for cellular health.

• Anti-inflammatory and Antioxidant Properties

UA exhibits anti-inflammatory and antioxidant effects, potentially contributing to its overall health benefits.

• Impact on Aging

Some research suggests UA may slow down or prevent age-related decline in muscle, brain, and other organs.

• Human Studies

Clinical trials in elderly individuals have shown potential benefits of UA supplementation on muscle health.

How to Increase Urolithin A Levels

• Diet

Consuming foods rich in ellagitannins and ellagic acid, like pomegranates, berries, and walnuts, can help increase UA production.

• Supplementation

Urolithin A supplements are available, and some studies suggest that supplementation can be more effective than relying solely on dietary sources.

Urolithin Optimal Formulation

• Antioxidants

Combining with antioxidants like resveratrol and quercetin boosts its ability to fight oxidative stress and aging.

• Vitamins

Vitamins C, E, and B enhance its antioxidant effects and support cellular health.

• Minerals

Magnesium, zinc, and selenium complement its benefits, supporting enzyme function and immunity.

• Coenzyme Q10

Works synergistically with Urolithin A to improve mitochondrial function and energy.

• Polyphenols

Curcumin and EGCG enhance anti-inflammatory and antioxidant effects.

• Omega-3 Fatty Acids

Supports cardiovascular health and cognitive function.

FAQs

Q1: How does UrolithinA work in the body?

A1: UrolithinA promotes mitophagy, the process of clearing damaged mitochondria, which enhances cellular energy production and muscle endurance.

Q2: What are the benefits of taking UrolithinA?

A2: Supplementing with UrolithinA may improve muscle strength, endurance, and reduce inflammation.

Q3: Are there any side effects of UrolithinA?

A3: UrolithinA is generally well tolerated. Some people may experience mild digestive discomfort, such as bloating or nausea, especially at higher doses.Taking with food can help minimize these effects.

Q4: How long does it take to experience the benefits of Urolithin A?

A4: Most people may notice improvements in muscle endurance and energy levels within 4-8 weeks of consistent use. Long-term benefits for metabolic health and aging are usually apparent after 12 weeks.

Q5: Can I take UrolithinA with other supplements or medications?

A5: UrolithinA can generally be taken with other supplements. However, it is recommended to consult a healthcare provider before combining it with other medications or supplements to ensure safety and avoid potential interactions.

Q6: Is UrolithinA FDA-approved?

A6: UrolithinA has not been approved by the FDA for specific medical treatments. However, the FDA has granted it Generally Recognized as Safe (GRAS) status as a dietary supplement, indicating that it is considered safe when used according to recommended guidelines.

Urolithin A Bulk OEM Manufacturer

Securing a reliable supply chain is the most critical step in scaling your health brand. As a direct factory specializing in high-purity Urolithin A, we provide the technical stability and volume capacity you need to stay ahead of market trends. Our production facility is fully backed by ISO, cGMP, and third-party lab certifications, ensuring every kilogram meets strict international safety and purity standards.

What sets our Urolithin A apart is our specialized micro-milling process, which solves the common industry challenge of poor solubility, giving your finished capsules or powders a clear functional advantage. Whether you need custom concentrations or large-scale bulk shipments, we have the infrastructure to support your growth from the first pilot batch to global distribution. Reach out to our team today to discuss wholesale pricing, request COAs, or start your private label project at info@botanicalsuppliers.com.