Product Name: Pyrroloquinoline Quinone (PQQ) Powder
Other Names: Pyrroloquinoline Quinone Acid, Pyrroloquinoline Quinone Disodium Salt
CAS No.: 72909-34-3
Specification: 98%, 99% Purity
Appearance: Deep Red Fine Powder
Test Method: HPLC
Certificates: ISO 22000, FSSC 22000, Kosher, Halal, Organic (EU), USDA, FDA, SGS
Sample: 10–50 g free sample available
MOQ: 1 kg
OEM Service: Private label and customized packaging available
Pyrroloquinoline Quinone, also known as PQQ or methoxatin, is a powerful bioactive compound widely used in dietary supplements for its potential to support cellular energy production and antioxidant defense. The primary active component, PQQ, plays a key role in mitochondrial function, helping to maintain healthy energy metabolism and reduce oxidative stress in the body.
In today’s nutraceutical market, PQQ powder has seen growing interest due to its applications in energy support formulations, cognitive health supplements, and anti-aging products. Manufacturers and supplement brands are increasingly seeking high-purity, consistent PQQ powders to meet rising consumer demand.
At Botanical Cube Inc., we focus on producing PQQ powder with stringent quality control and consistent bioactivity. Unlike generic suppliers, our PQQ retains high stability and purity, ensuring optimal effectiveness in formulations. Combined with our flexible OEM and private-label solutions, we help brands seamlessly integrate PQQ into their products with custom packaging, dosage options, and regulatory support, making the process simpler and more reliable than working with standard providers.
Whether for capsule, tablet, or powdered formulations, our PQQ powder is designed to meet the unique needs of modern supplement development while delivering reproducible quality across every batch.
1. Superior Stability in Formulations
Our proprietary microencapsulation minimizes PQQ degradation during high‑temperature processing and long-term storage, maintaining potency where many powders lose 20–30% activity.
2. Custom Particle & Solubility Design
Specific particle size ranges (D50: 10–80 µm) and solubility grades tailored for capsules, tablets, or beverages, ensuring smooth processing and consistent dissolution.
3. Optimized Functional Performance
Engineered to preserve bioactive PQQ in finished products, maximizing mitochondrial support and antioxidant activity in end formulations.
4. OEM-Ready Flexibility
Beyond supplying high-stability PQQ, we provide custom grades, packaging options, and formulation guidance, helping brands shorten development cycles and reduce batch failures.
| Item | Specification | Test Method | Result |
| Appearance | Reddish-brown fine powder | Visual | Reddish-brown fine powder |
| Odor | Characteristic | Organoleptic | Characteristic odor |
| Identification | PQQ positive | UV / HPLC | Conforms |
| Assay (PQQ content) | ≥99% | HPLC | 99.20% |
| Loss on Drying | ≤1.0% | 105°C / 2h | 0.50% |
| Residue on Ignition | ≤0.5% | AOAC 923.03 | 0.20% |
| Heavy Metals (As, Pb, Cd, Hg) | ≤10 ppm total | ICP-MS | As <1 ppm
Pb <0.5 ppm Cd <0.1 ppm Hg <0.1 ppm |
| Arsenic (As) | ≤2 ppm | ICP-MS | <1 ppm |
| Lead (Pb) | ≤2 ppm | ICP-MS | <0.5 ppm |
| Cadmium (Cd) | ≤1 ppm | ICP-MS | <0.1 ppm |
| Mercury (Hg) | ≤0.1 ppm | ICP-MS | <0.1 ppm |
| Microbial Limits | Total Plate Count ≤1000 CFU/g
Yeast & Mold ≤100 CFU/g E. coli / Salmonella / S. aureus Negative |
USP <2021> | Total Plate Count: 50 CFU/g
Yeast & Mold: 20 CFU/g Pathogens: Negative |
| Loss on Storage Stability | ≤2%/12 months @25°C, dark | Internal | 1.20% |
1. Energy & Mitochondrial Support
PQQ acts as a cofactor in mitochondrial biogenesis, supporting cellular energy production. Commonly used in capsules, tablets, and functional powders to enhance energy metabolism.
2. Cognitive Health Formulations
Included in supplements targeting memory, focus, and neuroprotection. Often combined with other nootropics like CoQ10, L-theanine, or alpha-lipoic acid to enhance efficacy.
3. Anti-Aging & Longevity Products
Its antioxidant properties help reduce oxidative stress, making it suitable for formulations aimed at healthy aging and cellular protection.
4. Functional Beverages & Powders
PQQ can be integrated into ready-to-drink beverages or powdered blends, but stability under heat, pH changes, and light must be carefully managed.
5. Combination Formulas
PQQ is frequently paired with NMN, resveratrol, or CoQ10 for synergistic mitochondrial support. Choosing the right grade and particle size is critical to maintain bioactivity in multi-ingredient blends.
1. Dietary Supplements
10–20 mg per serving is typical based on clinical studies and regulatory guidance.
2. Powdered or Beverage Applications
0.05–0.1% w/w depending on formulation stability, solubility, and intended serving size.
3. OEM/Custom Formulations
Dosage can be optimized based on synergistic ingredients, regulatory compliance in target markets, and desired functional outcomes.
1. Stability
PQQ is sensitive to heat, light, and pH. Microencapsulation, co-crystallization, or solubility-enhanced grades help maintain potency during processing and storage.
2. Solubility & Particle Size
Fine-tuned particle sizes (D50: 10–80 µm) improve dissolution and uniformity in powders, capsules, and liquids, reducing clumping and ensuring consistent dosing.
3. Bioavailability
Selecting the appropriate PQQ grade and solubility enhancement is essential to maximize mitochondrial and antioxidant activity in the final product.
4. Compatibility with Other Ingredients
PQQ can interact with minerals or highly acidic ingredients. Pre-formulated blends or customized grades reduce degradation and improve end-product stability.
1. How can I prevent PQQ degradation in capsules or beverages?
Use microencapsulated PQQ or co-crystallized forms and avoid high-temperature exposure during manufacturing.
2. Can PQQ be mixed with other antioxidants or energy compounds?
Yes, but consider solubility, pH, and processing conditions; custom OEM grades help maintain activity in complex formulas.
3. What dosage ensures efficacy while remaining safe?
10–20 mg per serving is widely used in adult supplements; always follow local regulatory guidelines.
4. How do I avoid clumping in powders?
Select particle size and flow properties optimized for your production process; anti-caking agents can also help.
Our PQQ Powder combines advanced processing stability with tailored particle and solubility options, ensuring optimal performance in capsules, tablets, or beverage blends. Certified for quality and safety, it provides brands a reliable ingredient for energy, cognitive, and anti-aging formulations. We support OEM partnerships with flexible supply, private-label services, and technical guidance for faster development and reduced risk. Start your collaboration today via
info@botanicalsuppliers.com.
Just send email to info@botanicalsuppliers.com, or submit your requirement in bottom form, we are of service at any time!
If you have any questions, please contact our experts.We are always ready to help you with individual formulations, private label solutions or any other requirements to kick-start your brand!