Tetrahydrocurcumin Powder

Product Description

What Is Tetrahydrocurcumin？

Tetrahydrocurcumin (THC) is a major metabolite of curcumin, a compound found in turmeric. It is known for its superior solubility, stability, and bioavailability compared to curcumin itself. Tetrahydrocurcumin exhibits antioxidant, anti-inflammatory, and potential anticancer and neuroprotective properties. It is also being explored for its potential in cosmetics and functional foods due to its skin-whitening and antioxidant effects.

Tetrahydrocurcumin is a natural functional whitening ingredient. Its potent tyrosinase inhibitory activity surpasses arbutin in whitening effectiveness. It effectively inhibits the generation of oxygen free radicals and scavenges existing free radicals, exhibiting significant antioxidant effects, such as anti-aging, skin repair, pigmentation reduction, and freckle removal. It is widely used in various skincare products for whitening, freckle removal, and antioxidant benefits, including creams, lotions, and serums.

Tetrahydrocurcumin Powder Specifications

Effects of Tetrahydrocurcumin

• Antioxidant and Anti-inflammatory

Tetrahydrocurcumin protects cells from damage by scavenging free radicals and inhibiting oxidative stress. Studies have shown that it can activate the Nrf2 antioxidant pathway, enhancing cellular defenses. Furthermore, by inhibiting inflammatory factors such as NF-κB and COX-2, it reduces chronic inflammation, potentially aiding in the treatment of conditions such as arthritis and enteritis.

• Skin Health

Whitening and Spot Reduction: Inhibits tyrosinase activity, reduces melanin production, and improves pigmentation.

Anti-Photoaging: Reduces UV-induced collagen degradation, delaying skin sagging and wrinkle formation.

Barrier Repair: Enhances the stratum corneum’s ability to retain moisture, alleviating dryness, sensitivity, and other skin problems.

Due to its mild nature, it is often used in anti-aging and anti-freckle skincare products.

• Liver Protection

Tetrahydrocurcumin promotes the activity of liver detoxification enzymes (such as glutathione S-transferase), helping to metabolize toxins. Experiments have shown that it can reduce liver damage caused by alcohol, drugs, or chemicals, maintain stable liver function by reducing lipid peroxidation and inhibiting liver fibrosis.

• Metabolic Regulation

Tetrahydrocurcumin can improve insulin sensitivity and help regulate blood sugar levels, making it beneficial for people with prediabetes. It can also lower blood triglyceride and low-density lipoprotein (LDL) levels, reducing the risk of atherosclerosis.

• Nervous System Protection

Animal studies have shown that tetrahydrocurcumin reduces beta-amyloid deposition and improves cognitive function through antioxidant and anti-inflammatory mechanisms, suggesting research value for neurodegenerative diseases such as Alzheimer’s disease.

Tetrahydrocurcumin VS Curcumin

Tetrahydrocurcumin (THC) is a metabolite of curcumin that offers better bioavailability and stability, making it potentially more effective for certain applications like anti-diabetic, anti-inflammatory, and anti-oxidative treatments. While both compounds share therapeutic properties, curcumin’s double bonds make it less stable under certain conditions, leading to a pro-oxidant effect, whereas Tetrahydrocurcumin’s reduced structure provides better solubility, stability, and antioxidant potential.

Key Differences

Structure:
Tetrahydrocurcumin is a reduced form of curcumin, lacking the double bonds found in curcumin’s structure.

Stability:
Tetrahydrocurcumin is more stable than curcumin, especially under basic conditions where curcumin can degrade.

Bioavailability:
Tetrahydrocurcumin has better bioavailability, meaning it is absorbed and utilized more effectively by the body than curcumin.

Antioxidant Activity:
Tetrahydrocurcumin is considered a potent antioxidant, with some studies suggesting it has superior antioxidant properties compared to curcumin.

Pro-oxidant Effects:
Under non-polar conditions, curcumin can exhibit a pro-oxidant effect, which is not seen with Tetrahydrocurcumin.

Applications of Tetrahydrocurcumin

• Cosmetic Applications

As a core whitening ingredient, it is used in:
Development of whitening essences, using nanotechnology to enhance transdermal absorption
Anti-aging cream formulations, synergistic with vitamin C derivatives
Anti-freckle product systems, reducing UV-induced hyperpigmentation

• Pharmaceutical and Food Applications

Pharmaceutical intermediates: used in the development of antioxidant drugs
Food additives: used as a natural pigment and functional ingredient
Health supplement raw materials: solid dispersion formulations for whitening applications

Tetrahydrocurcumin Powder Supplier And Manufacturer

BOTANICAL CUBE INC is a professional cosmetic raw material manufacturer with raw material developers to discover, refine and test ingredients used in cosmetic final products. Our R&D team has 17 years of R&D experience. The company has established 3 independent R&D centers with international standards and can customize all kinds of cosmetic raw materials.

We offers the different active ingredient which can be used for cosmetics.Our ingredients have antibacterial, antipruritic, moisturizing, anti-allergic, whitening, whitening, freckle removal, sun protection, anti-inflammatory and other functions.

How to buy Tetrahydrocurcumin Powder?

Just send an email to info@botanicalsuppliers.com, or submit your needs in the form at the bottom, we are always at your service!