Product Name:Nicotinamide Riboside Powder
Other Name:NR Powder
Appearance:White powder
Test Method:HPLC
Specification:99%
Sample:10-50g Sample For free
MOQ:1kg
Certificate:ISO22000, Kosher, Halal, EU, USDA, HACCP, FSSC 22000, Organic,FAD
OEM Service:Private label and Customized package
Nicotinamide riboside, or niagen, is a form of Vitamin B3 (frequently called niacin). You take in most of the nicotinamide riboside you need through your diet, but there might also be some health benefits to taking an extra dietary supplement.
NR serves as an intermediate building block to a very important coenzyme in your body called nicotinamide adenine dinucleotide (NAD+). All of the tissues in your body produce NAD+ from either NR or another common precursor called nicotinamide (NAM).
NAD+ levels decrease as you get older, particularly in the skin and brain, making it more challenging for the cells to produce enough energy to repair themselves. Taking an NR supplement can increase the NAD+ levels in your body’s tissues. Researchers think that this may help treat and prevent a wide variety of health conditions that happen with age.
NR is one of the most well-studied NAD+ precursors. It has been found to be safer, have better bioavailability, and be more effective at NAD+ synthesis than other precursors. NR may also avoid some of the common side effects of supplements that increase NAD+.
Research indicates NR is a potent anti-ageing molecule, helping to promote cellular longevity, protect DNA, and even prevent the development of certain diseases like Alzheimer’s, amyotrophic sclerosis (ALS), and Parkinson’s.
Product Name | Nicotinamide Riboside Powder |
Other Name | NR Powder |
Type | Food Grade |
Specification | 99% |
Appearance | White Powder |
Test Method | HPLC |
Certificate | ISO22000, Kosher, Halal, Organic(EU), USDA, FSSC 22000, FAD,SGS |
Sample | 10-50g Sample For free |
MOQ | 1kg |
OEM Service | Private label and Customized package |
Packaging | 1-5kg/25kg(aluminum foil bag/carton/cardboard drum) |
Shelf life | 2 year,Available InBulk, Private Label/OEM, Individually Packaged Goods |
The importance of NAD+ is reflected through the activity of NAD+-depleting enzymes, the mediators of aging, which are mostly induced by stress factors, such as DNA damage, oxidative stress, and inflammation. [6] It is a key regulator of cellular processes that control the body’s response to stress.
NAD+ allows cells to regenerate and repair, healing the body as it recovers from injuries and rigorous exercise. NAD+ is a sirtuin activator and sirtuin genes has the ability to repair cells and regress them to a more youthful state.
Supplementing with NR benefits people with NAD+ deficient so it’s more effective in older adults than younger people and has the potential extension of human lifespan.
With the increase of NAD+ levels in the body, nicotinamide riboside benefits metabolic regulation, energy storage and DNA synthesis. It kickstarts the metabolism, which burns fat, and helps the body regulate blood sugar levels.
It helps with metabolism and obesity by increasing lean muscle mass. Researchers conducted a randomized trial in which 13 otherwise healthy men and women who were overweight or obese were given either nicotinamide riboside 1000 mg/day or a placebo for six weeks.
Researchers have theorised that supplementing with NR may increase brain function and memory, protecting brain cells against oxidative stress that can cause age-related brain disorders.
NAD+ also increases the production of PGC-1-alpha, a protein that supports mitochondrial function, thus reducing the likelihood of cognitive dysfunction. When a person is NAD+ deficient, they are more likely to present with neuro-inflammation, DNA damage and neuronal degeneration in Alzheimer’s disease.
One study showed that using oral NR for six weeks beneficial for reducing blood pressure and arterial stiffness.
Studies have confirmed that an increase in NAD+ can help the body fight common viruses, bacteria, and fungi. It may also help improve hyper-inflammation from the immune system.
NAD+ helps control depression, anxiety and mood disorders. Researchers have demonstrated that people with low levels of NAD are at a higher risk for developing problems related to a range of mental disorders, including anxiety, addiction and depression.
Boosts energy levels and fights chronic fatigue, inserting itself into the energy cycle in your mitochondria of your cells that create energy.
NR supplements are generally considered to be safe. The upper tolerable intake for niacin is 35 mg daily, but only to avoid flushing.NR seldom causes flushing, so you can tolerate higher doses than recommended for niacin.
The FDA has suggested an upper limit of 180 mg per day for a person weighing 60 kilograms (kg), which is equivalent to 132 pounds, and comes out to 3 mg/kg of body weight per day.
The European Commission identified a UL of 900 mg per day. The Expert Group on Vitamins and Minerals in the United Kingdom (UK) identified a UL of 500 mg per day.
Studies in humans have used daily doses of up to 1,000 mg with no reported adverse effects.One study reported that NR supplements of 2,000 mg/day, divided into two daily dosages caused minor side effects such as sweating, itching, and bloating.
The FDA gave one NR supplement, Niagen, GRAS (generally recognized as safe) status.
Supplements similar to NR include the following:
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